LCE3D

Across TCGA patient cohorts, LCE3D protein abundance is significantly associated with the RNA expression of many other genes, with 8,372 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible LCE3D-associated genes across cancer lineages are CHRDL1, TGM5, and KLC3. Each is linked with LCE3D in more than 1 cancer types. Because this analysis shows association rather than direction, both LCE3D-to-partner and partner-to-LCE3D results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LCE3D versus CHRDL1 in HNSC, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LCE3D→partner) and Y-score (partner→LCE3D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CHRDL1 →	-1.204	-1.485	<.001	<.001	3	2
LSCC	TGM5 →	+0.868	+2.788	.003	.001	3	2
LSCC	KLC3 →	+0.862	+2.883	<.001	<.001	3	2
HNSC	CNFN →	+2.240	+1.760	<.001	<.001	3	2
LSCC	TSPAN12 →	-1.146	-3.210	<.001	<.001	3	2
LSCC	SPATA6L →	-0.630	-2.331	.005	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,372 associations by consensus.

LCE3D vs CHRDL1 — HNSC

Explore this scatter interactively →