LCE3D

Across TCGA pan-cancer cohorts, LCE3D RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of LCE3D’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where LCE3D RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LCE3D is over-expressed in tumor.

LUSC, HNSC, and PAAD are the cancer types where LCE3D tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LCE3D RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Male	All	+2.866	<.001	6	view →
HNSC	All	All	+1.636	.021	4	view →
PAAD	Male	All	+0.275	.025	2	view →
BRCA	All	All	+0.054	.040	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

LCE3D–LUSC

Open the LUSC breakdown →