LCE3D

Across TCGA cell cohorts, LCE3D RNA expression is significantly associated with the go_rna of many other GO terms, with 341 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible LCE3D-associated GO terms across cancer lineages are Regulation of proteolysis, Regulation of keratinocyte proliferation, and Positive regulation of protein depolymerization. Each is linked with LCE3D in more than 2 cancer types. Because this analysis shows association rather than direction, both LCE3D-to-partner and partner-to-LCE3D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of proteolysis grouped by LCE3D-low versus LCE3D-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LCE3D→partner) and Y-score (partner→LCE3D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of proteolysis →	+0.070	+0.078	<.001	.001	3	3
BLOOD_Lymphoma	Regulation of keratinocyte proliferation →	+0.048	+0.077	.001	.002	3	3
BLOOD_Lymphoma	Positive regulation of protein depolymerization →	-0.072	-0.106	.009	.003	3	3
BLOOD_Lymphoma	Regulation of pseudopodium assembly →	+0.095	+0.076	.003	.002	3	3
BLOOD_Lymphoma	Positive regulation of pseudopodium assembly →	+0.095	+0.076	.003	.002	3	3
BLOOD_Lymphoma	CD4-positive, alpha-beta T cell lineage commitment →	+0.130	+0.070	.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 341 associations by consensus.

Regulation of proteolysis by LCE3D expression — BLOOD_Lymphoma

Explore this box plot interactively →