LCE3C

Across TCGA patient cohorts, LCE3C RNA expression is significantly associated with the go_rna of many other GO terms, with 2,617 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible LCE3C-associated GO terms across cancer lineages are Regulation of antimicrobial humoral response, Regulation of antimicrobial peptide production, and Positive regulation of skeletal muscle tissue regeneration. Each is linked with LCE3C in more than 4 cancer types. Because this analysis shows association rather than direction, both LCE3C-to-partner and partner-to-LCE3C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of antimicrobial humoral response grouped by LCE3C-low versus LCE3C-high in SKCM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LCE3C→partner) and Y-score (partner→LCE3C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Regulation of antimicrobial humoral response →	+0.082	+0.277	<.001	<.001	3	5
SKCM	Regulation of antimicrobial peptide production →	+0.194	+0.276	<.001	<.001	3	5
ESCA	Positive regulation of skeletal muscle tissue regeneration →	+0.159	+0.384	<.001	<.001	3	5
SKCM	Gap junction assembly →	+0.038	+0.278	<.001	<.001	3	5
ESCA	Keratinization →	+0.139	+0.366	<.001	<.001	3	5
SKCM	Skin epidermis development →	+0.019	+0.503	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,617 associations by consensus.

Regulation of antimicrobial humoral response by LCE3C expression — SKCM

Explore this box plot interactively →