LCE3C

Across TCGA pan-cancer cohorts, LCE3C RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated LCE3C data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher LCE3C RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LCE3C expression acts as an unfavorable survival marker, although some lineages such as ESCA and CESC show a favorable association.

BLCA, BRCA, and LUSC are the cancer types where LCE3C RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	IV	0.262	0.622	<.001	129	view →
BRCA	DFS	Tertile	All	0.719	0.951	<.001	96	view →
LUSC	OS	Tertile	IV	0.001	0.673	.014	57	view →
ESCA	OS	Quartile	III,IV	0.751	0.470	.021	52	view →
SKCM	OS	Tertile	II,III,IV	0.161	0.340	<.001	51	view →
ACC	OS	Tertile	All	0.214	0.802	.002	45	view →
SCLC	OS	Tertile	All	0.055	0.708	<.001	36	view →
GBM	OS	Tertile	All	0.069	0.415	<.001	36	view →
CESC	DFS	Tertile	III,IV	0.898	0.643	.015	36	view →
KIRC	DFS	Tertile	All	0.260	0.796	.012	18	view →
SARC	OS	Tertile	All	0.197	0.526	.015	18	view →
STAD	DFS	Tertile	IV	0.097	0.412	.008	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

LCE3C–BLCA (OS)

Open the BLCA breakdown →