Across TCGA patient cohorts, LCE2C RNA expression is significantly associated with the go_rna of many other GO terms, with 5,120 significant associations in total. THCA shows the largest number of these associations.

The most reproducible LCE2C-associated GO terms across cancer lineages are Gap junction assembly, Regulation of antimicrobial peptide production, and Skin epidermis development. Each is linked with LCE2C in more than 6 cancer types. Because this analysis shows association rather than direction, both LCE2C-to-partner and partner-to-LCE2C results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LCE2C→partner) and Y-score (partner→LCE2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Gap junction assembly →	+0.047	+0.821	<.001	<.001	3	7
SKCM	Regulation of antimicrobial peptide production →	+0.253	+0.901	<.001	<.001	3	7
SKCM	Skin epidermis development →	+0.023	+0.661	<.001	<.001	3	6
ESCA	Peptidoglycan metabolic process →	+0.233	+0.427	<.001	<.001	3	6
SKCM	Regulation of antimicrobial humoral response →	+0.101	+0.923	<.001	<.001	3	6
SKCM	Positive regulation of antimicrobial humoral response →	+0.276	+0.952	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,120 associations by consensus.

Exploration

LCE2C survival (RNA) · tumor vs normal (RNA) · all LCE2C data types