LCE1F

Across TCGA patient cohorts, LCE1F mutation is significantly associated with the RNA expression of many other genes, with 315 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible LCE1F-associated genes across cancer lineages are KRTAP23-1, RN7SKP218, and RN7SKP83. Each is linked with LCE1F in more than 1 cancer types. Because this analysis shows association rather than direction, both LCE1F-to-partner and partner-to-LCE1F results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP23-1 grouped by LCE1F-low versus LCE1F-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LCE1F→partner) and Y-score (partner→LCE1F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	KRTAP23-1 →	+0.058	+3.199	<.001	.005	3	2
SKCM	RN7SKP218 →	+0.111	+4.095	<.001	<.001	3	2
LUSC	RN7SKP83 →	+0.269	+5.093	.004	.008	3	2
UCEC	MIR31 →	+0.445	+4.267	.002	.009	3	2
UCEC	RNU1-146P →	+0.433	+4.146	.001	.003	3	2
UCEC	RNA5SP205 →	+0.272	+4.267	.007	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 315 associations by consensus.

KRTAP23-1 by LCE1F expression — SKCM

Explore this box plot interactively →