LCE1F

Across TCGA pan-cancer cohorts, LCE1F RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated LCE1F data layer compared with 5 for mutation status.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher LCE1F RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LCE1F expression acts as an unfavorable survival marker, although some lineages such as ESCA and LUSC show a favorable association.

BLCA, KIRC, and KICH are the cancer types where LCE1F RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Tertile	All	0.181	0.378	<.001	130	view →
KIRC	DFS	Tertile	III,IV	0.176	0.650	<.001	114	view →
KICH	OS	Tertile	All	0.155	0.926	<.001	63	view →
BRCA	OS	Tertile	III,IV	0.600	0.910	.001	48	view →
STAD	OS	Quartile	IV	0.116	0.464	.001	42	view →
ESCA	OS	Median	II,III,IV	0.786	0.631	.017	42	view →
LUSC	DFS	Tertile	All	0.775	0.651	.003	33	view →
CHOL	DFS	Tertile	All	0.099	0.501	.015	24	view →
THCA	DFS	Tertile	All	0.085	0.811	<.001	9	view →
SKCM	OS	Tertile	IV	0.415	0.861	.014	9	view →
HNSC	OS	Median	All	0.500	0.321	.008	8	view →
LIHC	DFS	Tertile	II,III,IV	0.656	0.293	.032	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

LCE1F–BLCA (DFS)

Open the BLCA breakdown →