LCE1F

RNA expression — cross-omics
Cross-omicsRNA → MUTATIONCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, LCE1F RNA expression is significantly associated with the mutation status of many other genes, with 205 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LCE1F-associated genes across cancer lineages are SIPA1L2, PDE4B, and CDH7. Each is linked with LCE1F in more than 2 cancer types. Because this analysis shows association rather than direction, both LCE1F-to-partner and partner-to-LCE1F results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SIPA1L2 grouped by LCE1F-low versus LCE1F-high in LUNG_NSCLC_LUAD.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LCE1F→partner) and Y-score (partner→LCE1F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUADSIPA1L2 →+3.925+0.072<.001<.00133
BLOOD_MyelomaPDE4B →+4.807+0.166.006<.00132
OESOPHAGUSCDH7 →+4.906+0.330.006<.00132
OESOPHAGUSLAMB4 →+4.906+0.330.006<.00132
KIDNEYMYO9B →+5.000+0.226.005<.00132
LUNG_SCLCGOLGA3 →+4.058+0.086.007<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 205 associations by consensus.

SIPA1L2 by LCE1F expression — LUNG_NSCLC_LUAD

Box plot of SIPA1L2 in LCE1F-low vs LCE1F-high samples in LUNG_NSCLC_LUAD.

Explore this box plot interactively →

Exploration