LCE1D

Across TCGA patient cohorts, LCE1D RNA expression is significantly associated with the go_rna of many other GO terms, with 4,115 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible LCE1D-associated GO terms across cancer lineages are Intrinsic apoptotic signaling pathway in response to hydrogen peroxide, Thorax and anterior abdomen determination, and Positive regulation of vitamin D receptor signaling pathway. Each is linked with LCE1D in more than 4 cancer types. Because this analysis shows association rather than direction, both LCE1D-to-partner and partner-to-LCE1D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intrinsic apoptotic signaling pathway in response to hydrogen peroxide grouped by LCE1D-low versus LCE1D-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LCE1D→partner) and Y-score (partner→LCE1D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Intrinsic apoptotic signaling pathway in response to hydrogen peroxide →	+0.061	+0.060	<.001	.002	3	5
ESCA	Thorax and anterior abdomen determination →	+0.109	+0.136	<.001	.002	2	5
STAD	Positive regulation of vitamin D receptor signaling pathway →	+0.060	+0.070	<.001	<.001	3	4
HNSC	Regulation of antimicrobial humoral response →	+0.077	+0.797	<.001	<.001	3	4
SKCM	Antimicrobial peptide production →	+0.193	+0.681	<.001	<.001	3	4
STAD	Response to indole-3-methanol →	+0.063	+0.074	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,115 associations by consensus.

Intrinsic apoptotic signaling pathway in response to hydrogen peroxide by LCE1D expression — STAD

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