LCE1D

Across TCGA pan-cancer cohorts, LCE1D RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated LCE1D data layer compared with 1 for mutation status.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher LCE1D RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LCE1D expression acts as an unfavorable survival marker, although some lineages such as LGG and HNSC show a favorable association.

SKCM, LGG, and PCPG are the cancer types where LCE1D RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Tertile	All	0.811	0.893	.002	38	view →
LGG	OS	Median	All	0.876	0.747	<.001	36	view →
PCPG	DFS	Tertile	All	0.114	0.828	<.001	18	view →
SARC	OS	Tertile	All	0.261	0.734	.007	9	view →
LIHC	OS	Tertile	All	0.419	0.786	.009	9	view →
BLCA	DFS	Tertile	III,IV	0.279	0.455	.011	9	view →
HNSC	OS	Tertile	All	0.558	0.336	.005	5	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

LCE1D–SKCM (OS)

Open the SKCM breakdown →