LCE1D

Across TCGA patient cohorts, LCE1D mutation is significantly associated with the RNA expression of many other genes, with 68 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible LCE1D-associated genes across cancer lineages are MIR767, BCAS2P3, and DPP3P1. Each is linked with LCE1D in more than 1 cancer types. Because this analysis shows association rather than direction, both LCE1D-to-partner and partner-to-LCE1D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR767 grouped by LCE1D-low versus LCE1D-high in PRAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LCE1D→partner) and Y-score (partner→LCE1D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PRAD	MIR767 →	+0.238	+7.939	<.001	.008	3	2
LUSC	BCAS2P3 →	+0.064	+5.625	.003	.004	3	2
SKCM	DPP3P1 →	+0.029	+4.065	<.001	<.001	3	1
SKCM	RNU6-789P →	+0.272	+3.422	<.001	.006	3	1
SKCM	RGS21 →	+0.020	+3.869	<.001	<.001	3	1
SKCM	NIFKP8 →	+0.089	+2.748	.009	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 68 associations by consensus.

MIR767 by LCE1D expression — PRAD

Explore this box plot interactively →