Across TCGA patient cohorts, LCE1A RNA expression is significantly associated with the go_rna of many other GO terms, with 6,365 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LCE1A-associated GO terms across cancer lineages are Epidermal cell differentiation, Peptide cross-linking, and Regulation of antimicrobial humoral response. Each is linked with LCE1A in more than 6 cancer types. Because this analysis shows association rather than direction, both LCE1A-to-partner and partner-to-LCE1A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LCE1A→partner) and Y-score (partner→LCE1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Epidermal cell differentiation →	+0.065	+0.504	<.001	<.001	3	7
ESCA	Peptide cross-linking →	+0.127	+0.630	<.001	<.001	3	7
HNSC	Regulation of antimicrobial humoral response →	+0.101	+1.812	<.001	<.001	3	7
ESCA	Regulation of antimicrobial peptide production →	+0.157	+0.650	<.001	<.001	3	7
STAD	Intermediate filament-based process →	+0.047	+0.085	<.001	.002	3	6
ESCA	Integrin biosynthetic process →	+0.088	+0.518	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,365 associations by consensus.

Exploration

LCE1A survival (RNA) · tumor vs normal (RNA) · all LCE1A data types