Across TCGA patient cohorts, LCE1A mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LCE1A-associated genes across cancer lineages are CD8+ naive T-cells, Melanocytes, and Neurons. Each is linked with LCE1A in more than 1 cancer types. Because this analysis shows association rather than direction, both LCE1A-to-partner and partner-to-LCE1A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LCE1A→partner) and Y-score (partner→LCE1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ naive T-cells →	+0.045	+3.042	.004	.018	2	1
UCEC	Melanocytes →	-0.013	-2.946	.027	.037	2	1
UCEC	Neurons →	-0.024	-2.978	.028	.037	2	1
UCEC	pDC →	+0.064	+3.010	.022	.020	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

LCE1A survival (RNA) · tumor vs normal (RNA) · all LCE1A data types