Across TCGA cell cohorts, LCE1A mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LCE1A-associated genes across cancer lineages are LHCGR, CD300H, and SULT6B1. Each is linked with LCE1A in more than 1 cancer types. Because this analysis shows association rather than direction, both LCE1A-to-partner and partner-to-LCE1A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LCE1A→partner) and Y-score (partner→LCE1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	LHCGR →	+0.050	+4.467	<.001	.004	3	1
LARGE_INTESTINE	CD300H →	+0.033	+4.415	<.001	.007	3	1
LUNG_NSCLC_LUAD	SULT6B1 →	+1.618	+5.662	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

LCE1A survival (RNA) · tumor vs normal (RNA) · all LCE1A data types