LCA5L

Across TCGA cell cohorts, LCA5L RNA expression is significantly associated with the go_rna of many other GO terms, with 3,441 significant associations in total. CNS shows the largest number of these associations.

The most reproducible LCA5L-associated GO terms across cancer lineages are Cilium movement involved in cell motility, Protein localization to non-motile cilium, and Sperm motility. Each is linked with LCA5L in more than 13 cancer types. Because this analysis shows association rather than direction, both LCA5L-to-partner and partner-to-LCA5L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cilium movement involved in cell motility grouped by LCA5L-low versus LCA5L-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LCA5L→partner) and Y-score (partner→LCA5L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Cilium movement involved in cell motility →	-0.096	-0.618	.002	.002	2	14
OVARY	Protein localization to non-motile cilium →	+0.071	+0.574	.001	.005	3	13
LUNG_SCLC	Sperm motility →	-0.108	-0.578	.001	.003	3	13
BREAST	Protein localization to ciliary transition zone →	+0.071	+0.694	.001	.001	3	13
LUNG_SCLC	Flagellated sperm motility →	-0.108	-0.578	.001	.003	3	13
CNS	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.068	+0.577	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,441 associations by consensus.

Cilium movement involved in cell motility by LCA5L expression — LUNG_SCLC

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