LARP1

Across TCGA pan-cancer cohorts, LARP1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated LARP1 data layer compared with 25 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher LARP1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated LARP1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

CCRCC, UCEC, and LUAD are the cancer types where LARP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Tertile	All	0.775	0.974	.001	33	view →
UCEC	DFS	Tertile	III,IV	1.000	0.246	.011	24	view →
LUAD	DFS	Quartile	II,III,IV	0.215	0.706	.005	15	view →
PDAC	OS	Tertile	II,III,IV	0.389	0.716	.001	9	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

LARP1–CCRCC (OS)

Open the CCRCC breakdown →