LARP1

Across TCGA patient cohorts, LARP1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,941 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible LARP1-associated genes across cancer lineages are NHP2, NPM1, and HSPA9. Each is linked with LARP1 in more than 7 cancer types. Because this analysis shows association rather than direction, both LARP1-to-partner and partner-to-LARP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LARP1 versus NHP2 in UCEC, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LARP1→partner) and Y-score (partner→LARP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NHP2 →	+1.046	+0.188	.001	<.001	3	8
UCEC	NPM1 →	+0.965	+0.211	<.001	<.001	3	8
UCEC	HSPA9 →	+0.833	+0.206	<.001	<.001	3	7
UCEC	PRELID1 →	+0.720	+0.118	<.001	<.001	3	7
UCEC	HSPA4 →	+0.729	+0.198	<.001	<.001	3	7
UCEC	VDAC1 →	+0.817	+0.179	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,941 associations by consensus.

LARP1 vs NHP2 — UCEC

Explore this scatter interactively →