LARP1

Across TCGA cell cohorts, LARP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,958 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible LARP1-associated GO terms across cancer lineages are DNA-templated transcription initiation, DNA-templated transcription elongation, and Epigenetic regulation of gene expression. Each is linked with LARP1 in more than 16 cancer types. Because this analysis shows association rather than direction, both LARP1-to-partner and partner-to-LARP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated transcription initiation grouped by LARP1-low versus LARP1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LARP1→partner) and Y-score (partner→LARP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	DNA-templated transcription initiation →	+0.082	+0.871	<.001	.005	3	17
LIVER	DNA-templated transcription elongation →	+0.104	+0.773	.001	.002	3	16
UPPER_AERODIGESTIVE_TRACT	Epigenetic regulation of gene expression →	+0.065	+1.139	<.001	<.001	3	15
SOFT_TISSUE	DNA-templated transcription termination →	+0.092	+0.871	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Regulation of protein localization to centrosome →	+0.096	+1.073	<.001	.001	3	14
SOFT_TISSUE	Protein-DNA complex disassembly →	+0.122	+0.796	.003	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,958 associations by consensus.

DNA-templated transcription initiation by LARP1 expression — URINARY_TRACT

Explore this box plot interactively →