LAMC1

Across TCGA patient cohorts, LAMC1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,833 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible LAMC1-associated genes across cancer lineages are ADGRA2, MYCT1, and DIPK2B. Each is linked with LAMC1 in more than 9 cancer types. Because this analysis shows association rather than direction, both LAMC1-to-partner and partner-to-LAMC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LAMC1 versus ADGRA2 in OV, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LAMC1→partner) and Y-score (partner→LAMC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ADGRA2 →	+1.360	+0.477	<.001	<.001	3	10
BRCA	MYCT1 →	+0.743	+0.427	<.001	<.001	3	9
BRCA	DIPK2B →	+0.828	+0.489	<.001	<.001	3	9
GBM	BCL6B →	+0.841	+0.742	<.001	<.001	3	9
CCRCC	ADGRL4 →	+1.109	+0.628	<.001	<.001	3	9
LUAD	CLEC14A →	+0.865	+0.360	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,833 associations by consensus.

LAMC1 vs ADGRA2 — OV

Explore this scatter interactively →