LALBA

Across TCGA patient cohorts, LALBA mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible LALBA-associated genes across cancer lineages are Melanocytes, MEP, and Endothelial cells. Each is linked with LALBA in more than 1 cancer types. Because this analysis shows association rather than direction, both LALBA-to-partner and partner-to-LALBA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Melanocytes grouped by LALBA-low versus LALBA-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LALBA→partner) and Y-score (partner→LALBA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Melanocytes →	+0.058	+3.025	.032	.018	3	1
SKCM	MEP →	+0.031	+2.031	.010	.018	3	1
SKCM	Endothelial cells →	-0.042	-1.993	.016	.032	2	1
SKCM	lymphatic Endothelial cells →	-0.019	-3.237	.045	.007	2	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Melanocytes by LALBA expression — SKCM

Explore this box plot interactively →