LALBA

Across TCGA pan-cancer cohorts, LALBA RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated LALBA data layer compared with 3 for mutation status.

The strongest signal is observed in cholangiocarcinoma (CHOL), where higher LALBA RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LALBA expression acts as an unfavorable survival marker, although some lineages such as TGCT and HNSC show a favorable association.

CHOL, KIRP, and THYM are the cancer types where LALBA RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CHOL	OS	Tertile	All	0.024	0.728	<.001	108	view →
KIRP	DFS	Tertile	All	0.311	0.629	<.001	105	view →
THYM	OS	Tertile	All	0.676	0.907	<.001	87	view →
OV	DFS	Tertile	IV	0.243	0.502	.005	76	view →
ACC	OS	Tertile	All	0.519	0.847	.018	36	view →
UCS	DFS	Median	IV	0.440	0.885	.015	30	view →
KICH	DFS	Tertile	All	0.162	0.862	.014	21	view →
STAD	OS	Tertile	II,III,IV	0.372	0.602	.015	18	view →
TGCT	DFS	Median	All	0.922	0.737	.002	8	view →
HNSC	OS	Tertile	All	0.719	0.547	.035	4	view →
GBM	OS	Quartile	All	0.307	0.435	.041	3	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

LALBA–CHOL (OS)

Open the CHOL breakdown →