LALBA

Across TCGA pan-cancer cohorts, LALBA RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of LALBA’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LALBA RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LALBA is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.

KIRC, BRCA, and UCEC are the cancer types where LALBA tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LALBA RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.006	.003	7	view →
BRCA	Female	II,III,IV	−1.144	<.001	6	view →
UCEC	All	All	+0.063	.023	2	view →
LUSC	All	All	+0.028	.002	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

LALBA–KIRC

Open the KIRC breakdown →