LALBA

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, LALBA mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LALBA-associated genes across cancer lineages are KLHL34. Each is linked with LALBA in more than 1 cancer types. Because this analysis shows association rather than direction, both LALBA-to-partner and partner-to-LALBA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KLHL34 grouped by LALBA-low versus LALBA-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LALBA→partner) and Y-score (partner→LALBA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEKLHL34 →+0.117+3.793<.001.00731
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

KLHL34 by LALBA expression — LARGE_INTESTINE

Box plot of KLHL34 in LALBA-low vs LALBA-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration