Across TCGA patient cohorts, LAGE3 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,428 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LAGE3-associated proteins across cancer lineages are FAM50A, CSE1L, and MAGED2_S247. Each is linked with LAGE3 in more than 6 cancer types. Because this analysis shows association rather than direction, both LAGE3-to-partner and partner-to-LAGE3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LAGE3→partner) and Y-score (partner→LAGE3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FAM50A →	+0.418	+0.819	.001	<.001	3	7
LSCC	CSE1L →	+0.483	+0.838	<.001	<.001	3	6
LSCC	MAGED2_S247 →	+1.110	+0.672	<.001	<.001	3	6
OV	PHF6 →	+0.418	+0.658	.002	.007	2	7
OV	CUL4B →	+0.210	+0.521	<.001	.003	3	5
HNSC	HSPA14 →	+0.388	+1.433	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,428 associations by consensus.

Exploration

LAGE3 survival (RNA) · tumor vs normal (RNA) · all LAGE3 data types