Across TCGA cell cohorts, LAGE3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,740 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible LAGE3-associated GO terms across cancer lineages are Maintenance of translational fidelity, snRNA pseudouridine synthesis, and Positive regulation of telomerase RNA localization to Cajal body. Each is linked with LAGE3 in more than 18 cancer types. Because this analysis shows association rather than direction, both LAGE3-to-partner and partner-to-LAGE3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LAGE3→partner) and Y-score (partner→LAGE3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Maintenance of translational fidelity →	+0.144	+1.436	<.001	<.001	3	19
BONE	snRNA pseudouridine synthesis →	+0.109	+1.283	.001	<.001	3	11
PANCREAS	Positive regulation of telomerase RNA localization to Cajal body →	+0.105	+1.466	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Pyrimidine-containing compound biosynthetic process →	+0.122	+0.967	<.001	.007	3	11
BLOOD_Myeloma	Protein transmembrane transport →	+0.066	+1.062	<.001	.001	3	10
UPPER_AERODIGESTIVE_TRACT	Anatomical structure homeostasis →	-0.088	-1.066	<.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,740 associations by consensus.

Exploration

LAGE3 survival (RNA) · tumor vs normal (RNA) · all LAGE3 data types