L3MBTL2-AS1

associated omics data
L3MBTL2 antisense RNA 1Genealiases: []

Q-omics provides the consensus-scored L3MBTL2-AS1 profile across patient tissues and cancer cell-line models. L3MBTL2-AS1 expression is associated with patient survival in 20 of 34 cancer types, with the highest sampling consensus in LUAD. Among the 18 cancer types available for tumor–normal comparison, L3MBTL2-AS1 is differentially expressed in 11, with the highest sampling consensus in KICH. Additionally, L3MBTL2-AS1 RNA expression shows 20,723 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight LUAD, KICH, and TGCT as cancer lineages where L3MBTL2-AS1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes L3MBTL2-AS1 survival associations across molecular data types. L3MBTL2-AS1 RNA expression shows survival associations in the most cancer types (20). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
L3MBTL2-AS1 data typeSurvival analysisLineage consensusLineage of highest sampling consensus
RNAKaplan–Meier20LUAD (133)view →
This table ranks reproducible L3MBTL2-AS1 RNA expression–survival associations across cancer types. High L3MBTL2-AS1 expression shows unfavorable associations in ACC, KICH and LGG, but favorable associations in LUAD, HNSC and UCS. The LUAD Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify LUAD as the clearest survival context for L3MBTL2-AS1 RNA expression.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUADOSMedianAll0.7690.610<.001133view →
HNSCDFSMedianIV0.7250.555<.001130view →
ACCDFSTertileAll0.2660.729<.00168view →
UCSDFSQuartileIII,IV0.5810.096.00160view →
KICHDFSMedianIII,IV0.3731.000.00853view →
LGGOSTertileAll0.8520.943<.00132view →
Pink = unfavorable, green = favorable. all 20 lineages →

L3MBTL2-AS1-LUAD (OS)

Kaplan–Meier survival curve for L3MBTL2-AS1 RNA expression in LUAD: high vs low expression groups.

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Tumor vs Normal expression

This table summarizes L3MBTL2-AS1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 11. The strongest signals are observed in KICH for RNA.
L3MBTL2-AS1 data typeExpression analysisLineage consensusLineage of highest sampling consensus
RNABox plot11KICH (9)view →
This table ranks reproducible tumor–normal expression differences for L3MBTL2-AS1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. L3MBTL2-AS1 shows lower tumor expression in KICH, UCEC, BRCA and LUAD and higher tumor expression in HNSC and LIHC. The KICH box plot shows higher L3MBTL2-AS1 RNA expression in normal versus tumor tissue (log2 FC = −0.360, t-test p < 0.001).
LineageGenderStageFold-changepSampling consensus
KICHAllIII,IV−0.360<.0019view →
HNSCAllAll+0.425<.0017view →
UCECAllII,III,IV−0.640<.0016view →
BRCAAllIII,IV−0.507<.0016view →
LIHCMaleAll+0.291<.0016view →
LUADAllAll−0.272.0026view →
Green = repressed in tumor. all 11 lineages →

L3MBTL2-AS1-KICH

Tumor-vs-normal expression box plot for L3MBTL2-AS1 in KICH.

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Cross-omics associations

This table shows molecular features associated with L3MBTL2-AS1 in patient tissues and cancer cell lines. In patient samples, L3MBTL2-AS1 shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.
Associated data typeStrength (# associated data)Lineage of highest associated data
RNA
RNA20,723TGCT (7124)view →
Protein (mass-spec)9,420PDAC (2167)view →