KY

Across TCGA patient cohorts, KY protein abundance is significantly associated with the RNA expression of many other genes, with 430 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KY-associated genes across cancer lineages are SCML2, GDAP1, and RLN2. Each is linked with KY in more than 1 cancer types. Because this analysis shows association rather than direction, both KY-to-partner and partner-to-KY results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KY versus SCML2 in UCEC, with a Pearson correlation of -0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KY→partner) and Y-score (partner→KY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SCML2 →	-0.646	-0.601	.007	.006	3	1
UCEC	GDAP1 →	-0.446	-0.647	.003	.002	3	1
UCEC	RLN2 →	-0.562	-0.711	.007	.004	3	1
UCEC	RGS9 →	-0.459	-0.490	.002	.003	3	1
UCEC	MMD →	-0.782	-0.641	.009	.003	3	1
UCEC	SC5D →	-0.430	-0.665	.003	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 430 associations by consensus.

KY vs SCML2 — UCEC

Explore this scatter interactively →