Across TCGA patient cohorts, KRTDAP mutation is significantly associated with the RNA expression of many other genes, with 61 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible KRTDAP-associated genes across cancer lineages are OR7E53P, NUTF2P8, and MIR6801. Each is linked with KRTDAP in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTDAP-to-partner and partner-to-KRTDAP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTDAP→partner) and Y-score (partner→KRTDAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	OR7E53P →	+0.095	+4.344	<.001	.002	3	2
UCEC	NUTF2P8 →	+0.286	+4.567	<.001	.001	3	1
UCEC	MIR6801 →	+0.965	+4.221	<.001	.003	3	1
SKCM	MIR6124 →	+0.329	+3.717	<.001	.005	3	1
SKCM	PRSS47 →	+0.124	+3.490	<.001	.008	3	1
SKCM	FAM247B →	+0.217	+3.578	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 61 associations by consensus.

Exploration

KRTDAP survival (RNA) · tumor vs normal (RNA) · all KRTDAP data types