KRTAP8-1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KRTAP8-1 mutation is significantly associated with the RNA expression of many other genes, with 190 significant associations in total. COAD shows the largest number of these associations.

The most reproducible KRTAP8-1-associated genes across cancer lineages are OR10AG1, RTL4, and ATF1P1. Each is linked with KRTAP8-1 in more than 2 cancer types. Because this analysis shows association rather than direction, both KRTAP8-1-to-partner and partner-to-KRTAP8-1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP8-1→partner) and Y-score (partner→KRTAP8-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADOR10AG1 →+0.902+6.917<.001<.00133
COADRTL4 →+0.801+5.790<.001.00332
COADATF1P1 →+0.889+6.392<.001.00132
COADLINC02386 →+0.737+6.917<.001<.00132
COADEIF4A3P1 →+1.195+6.547<.001.00132
COADCYP4F10P →+0.790+5.283<.001.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 190 associations by consensus.

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