KRTAP5-9

Across TCGA cell cohorts, KRTAP5-9 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,892 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible KRTAP5-9-associated GO terms across cancer lineages are Regulation of transcription initiation by RNA polymerase II, Regulation of nucleocytoplasmic transport, and Regulation of DNA-templated transcription initiation. Each is linked with KRTAP5-9 in more than 8 cancer types. Because this analysis shows association rather than direction, both KRTAP5-9-to-partner and partner-to-KRTAP5-9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of transcription initiation by RNA polymerase II grouped by KRTAP5-9-low versus KRTAP5-9-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP5-9→partner) and Y-score (partner→KRTAP5-9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Regulation of transcription initiation by RNA polymerase II →	+0.028	+0.038	.007	.005	3	9
CNS	Regulation of nucleocytoplasmic transport →	+0.049	+0.064	.003	.001	3	8
LUNG_NSCLC_LUAD	Regulation of DNA-templated transcription initiation →	+0.031	+0.093	.002	.002	3	7
UPPER_AERODIGESTIVE_TRACT	Regulation of pattern recognition receptor signaling pathway →	+0.052	+0.138	.002	.001	3	7
BONE	Nucleic acid transport →	+0.093	+0.167	.005	.007	3	7
BONE	RNA transport →	+0.093	+0.167	.005	.007	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,892 associations by consensus.

Regulation of transcription initiation by RNA polymerase II by KRTAP5-9 expression — CNS

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