KRTAP5-9

Across TCGA pan-cancer cohorts, KRTAP5-9 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated KRTAP5-9 data layer compared with 5 for mutation status.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher KRTAP5-9 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated KRTAP5-9 expression acts as an unfavorable survival marker, although some lineages such as BLCA and STAD show a favorable association.

BLCA, DLBC, and STAD are the cancer types where KRTAP5-9 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Quartile	All	0.534	0.378	.001	55	view →
DLBC	DFS	Tertile	II,III,IV	0.603	1.000	.012	35	view →
STAD	OS	Quartile	III,IV	0.833	0.474	.004	34	view →
LGG	DFS	Median	All	0.780	0.876	<.001	34	view →
COAD	OS	Median	III,IV	0.685	0.888	.003	27	view →
THYM	DFS	Median	All	0.949	0.619	<.001	25	view →
THCA	OS	Median	II,III,IV	1.000	0.317	<.001	25	view →
PRAD	DFS	Tertile	All	0.805	0.929	<.001	20	view →
LUAD	DFS	Tertile	IV	0.507	0.976	.024	19	view →
CESC	OS	Quartile	IV	0.651	0.258	.034	18	view →
HNSC	OS	Tertile	II,III,IV	0.745	0.599	.011	16	view →
BRCA	OS	Quartile	III,IV	0.942	0.801	.007	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

KRTAP5-9–BLCA (DFS)

Open the BLCA breakdown →