KRTAP5-8

Across TCGA patient cohorts, KRTAP5-8 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,036 significant associations in total. STAD shows the largest number of these associations.

The most reproducible KRTAP5-8-associated GO terms across cancer lineages are Macromolecule deacylation, Protein deacetylation, and Positive regulation of sphingolipid biosynthetic process. Each is linked with KRTAP5-8 in more than 21 cancer types. Because this analysis shows association rather than direction, both KRTAP5-8-to-partner and partner-to-KRTAP5-8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Macromolecule deacylation grouped by KRTAP5-8-low versus KRTAP5-8-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP5-8→partner) and Y-score (partner→KRTAP5-8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Macromolecule deacylation →	+0.061	+0.489	<.001	<.001	3	22
STAD	Protein deacetylation →	+0.055	+0.198	<.001	<.001	3	21
BLCA	Positive regulation of sphingolipid biosynthetic process →	+0.046	+0.515	<.001	<.001	3	20
STAD	Regulation of DNA strand elongation →	+0.054	+0.124	<.001	<.001	3	18
STAD	Obsolete regulation of histone modification →	+0.057	+0.173	<.001	<.001	3	17
STAD	Macromolecule methylation →	+0.055	+0.213	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,036 associations by consensus.

Macromolecule deacylation by KRTAP5-8 expression — ESCA

Explore this box plot interactively →