Across TCGA patient cohorts, KRTAP5-5 mutation is significantly associated with the total protein of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP5-5-associated genes across cancer lineages are ASNS, EGFR_pY1068, and A-Raf_pS299. Each is linked with KRTAP5-5 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP5-5-to-partner and partner-to-KRTAP5-5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP5-5→partner) and Y-score (partner→KRTAP5-5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.503	+2.321	.005	.035	3	2
UCEC	EGFR_pY1068 →	-0.327	-2.321	.009	.035	3	1
UCEC	A-Raf_pS299 →	-0.131	-3.169	.028	.019	3	1
UCEC	Gab2 →	+0.545	+3.000	.002	.036	3	1
UCEC	Ku80 →	+0.292	+2.335	.013	.020	3	1
UCEC	Notch1 →	+0.280	+3.459	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

Exploration

KRTAP5-5 survival (RNA) · tumor vs normal (RNA) · all KRTAP5-5 data types