Across TCGA cell cohorts, KRTAP5-5 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible KRTAP5-5-associated genes across cancer lineages are OR14A16, KRTAP5-11, and OR2A25. Each is linked with KRTAP5-5 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP5-5-to-partner and partner-to-KRTAP5-5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP5-5→partner) and Y-score (partner→KRTAP5-5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR14A16 →	+0.014	+4.415	<.001	.007	3	1
SKIN	KRTAP5-11 →	+0.041	+4.684	<.001	.002	3	1
SKIN	OR2A25 →	+0.048	+4.467	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

KRTAP5-5 survival (RNA) · tumor vs normal (RNA) · all KRTAP5-5 data types