Across TCGA patient cohorts, KRTAP5-11 mutation is significantly associated with the total protein of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP5-11-associated genes across cancer lineages are 14-3-3_beta, HSP70, and JNK_pT183_Y185. Each is linked with KRTAP5-11 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP5-11-to-partner and partner-to-KRTAP5-11 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP5-11→partner) and Y-score (partner→KRTAP5-11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	14-3-3_beta →	-0.097	-2.973	.032	.035	3	1
UCEC	HSP70 →	-0.377	-2.990	.037	.036	3	1
UCEC	JNK_pT183_Y185 →	-0.172	-1.986	.023	.032	3	1
UCEC	p62 Lck ligand →	+0.366	+3.009	.012	.019	3	1
UCEC	PDK1_pS241 →	+0.218	+2.013	.004	.018	3	1
UCEC	Annexin-1 →	+0.631	+2.341	.007	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration

KRTAP5-11 survival (RNA) · tumor vs normal (RNA) · all KRTAP5-11 data types