Across TCGA patient cohorts, KRTAP4-6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,581 significant associations in total. STAD shows the largest number of these associations.

The most reproducible KRTAP4-6-associated GO terms across cancer lineages are Positive regulation of small GTPase mediated signal transduction, Cytoskeleton-dependent intracellular transport, and Negative regulation of cell development. Each is linked with KRTAP4-6 in more than 6 cancer types. Because this analysis shows association rather than direction, both KRTAP4-6-to-partner and partner-to-KRTAP4-6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP4-6→partner) and Y-score (partner→KRTAP4-6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of small GTPase mediated signal transduction →	+0.045	+0.060	<.001	<.001	3	5
STAD	Cytoskeleton-dependent intracellular transport →	+0.062	+0.103	<.001	<.001	2	6
READ	Negative regulation of cell development →	+0.023	+0.026	<.001	.008	1	7
PAAD	Sphingosine-1-phosphate receptor signaling pathway →	+0.057	+0.057	<.001	.001	3	5
STAD	DNA strand resection involved in replication fork processing →	+0.061	+0.075	<.001	.001	3	5
LGG	Regulation of attachment of mitotic spindle microtubules to kinetochore →	+0.128	+0.006	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,581 associations by consensus.

Exploration

KRTAP4-6 survival (RNA) · tumor vs normal (RNA) · all KRTAP4-6 data types