Across TCGA cell cohorts, KRTAP4-6 RNA expression is significantly associated with the go_rna of many other GO terms, with 472 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KRTAP4-6-associated GO terms across cancer lineages are Lipid oxidation, Positive regulation of fibroblast proliferation, and Negative regulation of appetite by leptin-mediated signaling pathway. Each is linked with KRTAP4-6 in more than 3 cancer types. Because this analysis shows association rather than direction, both KRTAP4-6-to-partner and partner-to-KRTAP4-6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP4-6→partner) and Y-score (partner→KRTAP4-6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Lipid oxidation →	-0.048	-0.193	.001	.006	3	4
LARGE_INTESTINE	Positive regulation of fibroblast proliferation →	+0.099	+0.232	<.001	.007	3	4
LUNG_NSCLC_LUAD	Negative regulation of appetite by leptin-mediated signaling pathway →	-0.125	-0.031	<.001	.005	3	3
LARGE_INTESTINE	Regulation of cytokine-mediated signaling pathway →	+0.041	+0.231	.001	.009	3	3
LARGE_INTESTINE	Response to psychosocial stress →	+0.505	+0.233	.001	.009	3	3
LARGE_INTESTINE	Regulation of hepatic stellate cell activation →	-0.251	-0.260	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 472 associations by consensus.

Exploration

KRTAP4-6 survival (RNA) · tumor vs normal (RNA) · all KRTAP4-6 data types