KRTAP4-2

Across TCGA patient cohorts, KRTAP4-2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,400 significant associations in total. STAD shows the largest number of these associations.

The most reproducible KRTAP4-2-associated GO terms across cancer lineages are Spermatid nucleus differentiation, Positive regulation of sequestering of calcium ion, and Skeletal muscle acetylcholine-gated channel clustering. Each is linked with KRTAP4-2 in more than 3 cancer types. Because this analysis shows association rather than direction, both KRTAP4-2-to-partner and partner-to-KRTAP4-2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Spermatid nucleus differentiation grouped by KRTAP4-2-low versus KRTAP4-2-high in KIRP.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP4-2→partner) and Y-score (partner→KRTAP4-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRP	Spermatid nucleus differentiation →	+0.051	+0.008	<.001	.002	3	3
STAD	Positive regulation of sequestering of calcium ion →	+0.076	+0.078	<.001	<.001	3	3
STAD	Skeletal muscle acetylcholine-gated channel clustering →	+0.075	+0.035	<.001	.001	3	3
STAD	Regulation of protein serine/threonine kinase activity →	+0.070	+0.058	<.001	<.001	3	3
ESCA	Double-strand break repair via classical nonhomologous end joining →	+0.040	+0.078	<.001	.003	2	4
STAD	Mitochondrial translation →	+0.113	+0.073	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,400 associations by consensus.

Spermatid nucleus differentiation by KRTAP4-2 expression — KIRP

Explore this box plot interactively →