KRTAP4-2

Across TCGA pan-cancer cohorts, KRTAP4-2 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of KRTAP4-2’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where KRTAP4-2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KRTAP4-2 is over-expressed in tumor.

LUSC are the cancer types where KRTAP4-2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KRTAP4-2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	II,III,IV	+0.019	.044	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

KRTAP4-2–LUSC

Open the LUSC breakdown →