Across TCGA patient cohorts, KRTAP4-11 mutation is significantly associated with the RNA expression of many other genes, with 436 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP4-11-associated genes across cancer lineages are RN7SL760P, RNA5SP434, and AHCYP7. Each is linked with KRTAP4-11 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP4-11-to-partner and partner-to-KRTAP4-11 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP4-11→partner) and Y-score (partner→KRTAP4-11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	RN7SL760P →	+0.182	+3.915	<.001	.005	3	1
LIHC	RNA5SP434 →	+0.245	+3.690	.002	.009	3	1
LIHC	AHCYP7 →	+0.032	+4.014	<.001	.004	3	1
LIHC	MIR4444-2 →	+0.421	+4.119	<.001	.004	3	1
UCEC	HSPE1-MOB4 →	+0.170	+2.584	.002	.002	3	1
UCEC	IGHV3OR16-6 →	+0.529	+2.245	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 436 associations by consensus.

Exploration

KRTAP4-11 survival (RNA) · tumor vs normal (RNA) · all KRTAP4-11 data types