Across TCGA pan-cancer cohorts, KRTAP4-11 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of KRTAP4-11’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where KRTAP4-11 RNA is repressed in tumor relative to normal tissue. In most cancer types KRTAP4-11 is over-expressed in tumor, although a few such as BRCA and THCA show the opposite, repressed pattern.

BRCA and THCA are the cancer types where KRTAP4-11 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KRTAP4-11 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	III,IV	−0.036	.014	2	view →
THCA	All	All	−0.020	.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: KRTAP4-11 RNA expression & survival · all KRTAP4-11 data types