Across TCGA patient cohorts, KRTAP4-11 mutation is significantly associated with the total protein of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP4-11-associated genes across cancer lineages are FOXO3a, ERK2, and FOXO3a_pS318_S321. Each is linked with KRTAP4-11 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP4-11-to-partner and partner-to-KRTAP4-11 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP4-11→partner) and Y-score (partner→KRTAP4-11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FOXO3a →	-0.121	-3.156	.029	.020	3	2
UCEC	ERK2 →	+0.243	+3.000	.021	.036	3	1
UCEC	FOXO3a_pS318_S321 →	-0.172	-3.169	.012	.020	3	1
UCEC	GAPDH →	+0.664	+3.169	.024	.020	3	1
UCEC	JNK_pT183_Y185 →	-0.204	-3.156	.027	.020	3	1
UCEC	mTOR_pS2448 →	-0.225	-3.169	.005	.020	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration

KRTAP4-11 survival (RNA) · tumor vs normal (RNA) · all KRTAP4-11 data types