KRTAP3-2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KRTAP3-2 mutation is significantly associated with the RNA expression of many other genes, with 98 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP3-2-associated genes across cancer lineages are CHEK2P5, MTCO2P32, and HIGD1AP15. Each is linked with KRTAP3-2 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP3-2-to-partner and partner-to-KRTAP3-2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP3-2→partner) and Y-score (partner→KRTAP3-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADCHEK2P5 →+0.243+5.003.004.00432
COADMTCO2P32 →+0.361+5.392<.001.00232
UCECHIGD1AP15 →+0.242+3.833<.001.00132
UCECCOX6CP11 →+0.330+4.005<.001.00232
COADRNA5SP500 →+0.424+5.721.008.00131
COADATXN7L3P1 →+0.118+4.717.006.00331
Each partner links to its Q-omics profile. Showing the 6 strongest of 98 associations by consensus.

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