Across TCGA pan-cancer cohorts, KRTAP3-2 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of KRTAP3-2’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where KRTAP3-2 RNA is repressed in tumor relative to normal tissue. In most cancer types KRTAP3-2 is over-expressed in tumor, although a few such as HNSC and STAD show the opposite, repressed pattern.

HNSC, COAD, and UCEC are the cancer types where KRTAP3-2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KRTAP3-2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	All	−1.105	<.001	10	view →
COAD	All	All	+0.201	.002	4	view →
UCEC	All	All	+0.054	.048	2	view →
STAD	All	All	−0.915	.048	1	view →
KIRP	All	All	+0.017	.049	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: KRTAP3-2 RNA expression & survival · all KRTAP3-2 data types