KRTAP26-1

mutation — cross-omics
Cross-omicsMUTATION → MUTATIONCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, KRTAP26-1 mutation is significantly associated with the mutation status of many other genes, with 2,614 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KRTAP26-1-associated genes across cancer lineages are GRIN3A, TBK1, and MTUS1. Each is linked with KRTAP26-1 in more than 2 cancer types. Because this analysis shows association rather than direction, both KRTAP26-1-to-partner and partner-to-KRTAP26-1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP26-1→partner) and Y-score (partner→KRTAP26-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaGRIN3A →+4.584+4.584.007.00713
BLOOD_LeukemiaTBK1 →+4.560+4.309.007.00713
LUNG_NSCLC_LUADMTUS1 →+4.772+5.339.004.00413
LUNG_NSCLC_LUADADAMTS14 →+4.187+5.000.008.00813
LUNG_NSCLC_LUADPHIP →+4.187+5.000.008.00813
LUNG_NSCLC_LUADMFHAS1 →+5.772+5.772.002.00213
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,614 associations by consensus.

Exploration