Across TCGA patient cohorts, KRTAP21-2 mutation is significantly associated with the RNA expression of many other genes, with 44 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible KRTAP21-2-associated genes across cancer lineages are RN7SL571P, TTTY7B, and USP9YP6. Each is linked with KRTAP21-2 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP21-2-to-partner and partner-to-KRTAP21-2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP21-2→partner) and Y-score (partner→KRTAP21-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RN7SL571P →	+0.276	+4.993	<.001	.003	3	2
LGG	TTTY7B →	+0.029	+7.977	<.001	.007	3	1
LGG	USP9YP6 →	+0.049	+7.977	<.001	.007	3	1
UCEC	RNU6-467P →	+0.390	+5.722	<.001	.001	3	1
LUAD	RNU6-650P →	+0.553	+5.157	<.001	.007	3	1
LUAD	LINC01044 →	+0.164	+5.481	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 44 associations by consensus.

Exploration

KRTAP21-2 survival (RNA) · tumor vs normal (RNA) · all KRTAP21-2 data types