Across TCGA patient cohorts, KRTAP21-1 mutation is significantly associated with the RNA expression of many other genes, with 36 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible KRTAP21-1-associated genes across cancer lineages are MIR5693, RN7SL601P, and KRTAP10-8. Each is linked with KRTAP21-1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP21-1-to-partner and partner-to-KRTAP21-1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP21-1→partner) and Y-score (partner→KRTAP21-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR5693 →	+0.697	+4.132	<.001	<.001	3	1
SKCM	RN7SL601P →	+0.163	+7.816	<.001	.008	3	1
LUAD	KRTAP10-8 →	+0.030	+5.108	<.001	.002	3	1
LUAD	MTATP6P7 →	+0.030	+4.912	<.001	.003	3	1
LUAD	LINC01210 →	+0.675	+4.434	<.001	.001	3	1
LUAD	CYP4F34P →	+1.142	+3.681	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

Exploration

KRTAP21-1 survival (RNA) · tumor vs normal (RNA) · all KRTAP21-1 data types