Across TCGA pan-cancer cohorts, KRTAP21-1 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of KRTAP21-1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where KRTAP21-1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KRTAP21-1 is over-expressed in tumor.

KIRC are the cancer types where KRTAP21-1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KRTAP21-1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	+0.010	.044	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: KRTAP21-1 RNA expression & survival · all KRTAP21-1 data types