Across TCGA cell cohorts, KRTAP21-1 RNA expression is significantly associated with the mutation status of many other genes, with 75 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible KRTAP21-1-associated genes across cancer lineages are ITIH6, CCDC93, and PDE11A. Each is linked with KRTAP21-1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP21-1-to-partner and partner-to-KRTAP21-1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP21-1→partner) and Y-score (partner→KRTAP21-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	ITIH6 →	+3.700	+0.021	.009	<.001	3	1
SKIN	CCDC93 →	+5.022	+0.037	.002	<.001	3	1
SKIN	PDE11A →	+4.437	+0.030	.004	<.001	3	1
SKIN	EIF2B5 →	+6.022	+0.050	.001	<.001	3	1
SKIN	ZMYM4 →	+4.437	+0.030	.004	<.001	3	1
SKIN	APLF →	+6.022	+0.050	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 75 associations by consensus.

Exploration

KRTAP21-1 survival (RNA) · tumor vs normal (RNA) · all KRTAP21-1 data types